Telehealth Business Guides
Plain-language guides to what it actually takes to launch and run a telehealth brand: compliance, pharmacies, clinician partners and the numbers. Written by operators, with sources.
Tools
Calculator
Telehealth Profit Calculator
Model a subscription telehealth brand month by month: margin, churn, cost to acquire a patient, lifetime value and payback.
Calculator
Telehealth Launch Cost Estimator
What it costs to start a telehealth brand on a white-label partner, and how many patients you need to break even. Published 2026 vendor prices as defaults.
Start here
Partners
OpenLoop Alternatives: Telehealth Infrastructure Partners Compared (2026)
OpenLoop, Beluga Health, MD Integrations, Wheel, SteadyMD, Qualiphy, Telegra, CareValidate, Bask, Healthie and LifeFile: what each one actually provides, who supplies the medical group, published pricing, and how to choose.
Verticals
Which Telehealth Niche to Launch In (2026): Prices, Margins, Retention and Rules for 7 Verticals
GLP-1 weight loss, TRT, menopause, hair loss, ED, Rx skincare and longevity compared: what patients pay across 179 brands, generic cost of goods, how long patients stay, and the regulatory traps in each.
Launch guides by vertical
Vertical guide
How to Start a GLP-1 Weight Loss Telehealth Brand in 2026
Launching a GLP-1 weight-loss brand now: branded vs compounded medications, what 73+ brands charge, manufacturer self-pay prices, retention, labs, and the FDA and FTC rules that decide whether you survive.
Vertical guide
How to Start a TRT Telehealth Business in 2026 (and Plan for the DEA Deadline)
Launching a testosterone or men's health telehealth brand: Schedule III rules and the December 31, 2026 DEA deadline, the labs guidelines require, what brands charge, retention, enclomiphene's grey zone and claim rules.
Vertical guide
How to Start a Menopause and HRT Telehealth Brand in 2026
Launching a menopause care brand after FDA's 2025 hormone therapy label changes: approved vs compounded hormones, what brands charge, cost of goods, visit models and the claims to avoid.
Vertical guide
How to Start a Hair Loss Telehealth Brand in 2026
Launching a hair loss brand: finasteride, minoxidil and compounded combos, what brands charge, cost of goods under a dollar, FDA's 2025 alert on topical finasteride, and how to build margin in a low-price category.
Vertical guide
How to Start an ED Telehealth Brand in 2026
Launching an erectile dysfunction brand: generic vs compounded products, what 40 brands charge, pennies-per-pill cost of goods, retention, FDA's 2025 warning letter to BlueChew and subscription rules.
Vertical guide
How to Start a Prescription Skincare Telehealth Brand in 2026
Launching a prescription skincare brand: tretinoin and custom compounded creams, what brands charge, cost of goods, why isotretinoin can't run fully online, and the claims that keep you compliant.
Vertical guide
How to Start a Longevity Telehealth Clinic in 2026: NAD+, Rapamycin, Sermorelin
Launching a longevity telehealth brand: NAD+, sermorelin, rapamycin, metformin and LDN, what 59 brands charge, the evidence behind each, safety warnings, labs and the claims the FTC won't accept.
Compliance and regulation
Compliance
LegitScript Certification for Telehealth: Cost, Timeline and What Gets Rejected
What LegitScript certification is, when a telehealth brand needs it (Google, Meta, card processing), what it costs in 2026, the nine standards, and the issues that hold applications up.
Pharmacy
503A vs 503B Compounding Pharmacies, and What's Legal for Compounded GLP-1s in 2026
How 503A pharmacies and 503B outsourcing facilities differ, which one a telehealth brand uses, where compounded semaglutide and tirzepatide stand in October 2026, and the marketing claims FDA keeps citing.
Legal structure
Friendly PC and MSO Structures for Telehealth: How a Non-Doctor Owns a Telehealth Brand
Why a lay-owned telehealth brand usually can't employ doctors, how the MSO and friendly PC model works, which states are strict, the 2025–2026 law changes, and the prescribing rules that come with it.
Peptides
How to Start a Peptide Telehealth Business Legally (2026): Which Peptides Are Allowed
Which peptides a US telehealth brand can prescribe and have compounded as of October 2026, what Category 1 and Category 2 mean, where BPC-157 and TB-500 stand, why research peptides are off limits, and the compliant way to launch.
By business type
For med spas
Adding a GLP-1 or Peptide Program to Your Med Spa: Ownership, Supervision and Sourcing (2026)
What a med spa needs to offer GLP-1 weight loss or peptides compliantly: who can own it, medical director and good-faith exam rules in California, Texas and Florida, lawful drug sourcing, and the pitfalls regulators are acting on.
For gyms & coaches
GLP-1 Programs for Gyms, Trainers and Coaches: What You Can Legally Offer (2026)
How gyms, personal trainers, coaches and fitness creators can add GLP-1 and wellness telehealth programs: the six models clubs use, what a non-clinician business may and may not do, and why per-patient referral fees are the biggest legal risk.
For NPs & PAs
Starting a Cash-Pay Telehealth Practice as a Nurse Practitioner or PA (2026)
Full practice authority states, collaboration rules for NPs and PAs, the licensure compacts, prescribing controlled substances after the DEA's 2026 deadline, and what a collaborating physician costs.
Teardowns
Teardown
How Hims & Hers Makes Money, and What a Smaller Telehealth Brand Can Copy
A teardown of Hims & Hers from its SEC filings: revenue and margins from 2019 to 2026, how subscriptions, personalized plans and its own pharmacies work, the medical group structure, the GLP-1 saga, and which parts a niche brand can copy.
Teardown
How MEDVi Works: The Telehealth Business Model Behind the Two-Person GLP-1 Brand
A sourced teardown of MEDVi: what it sells, the clinician networks and pharmacies behind it, how it grew, the FDA warning letter and press backlash, and what a new telehealth brand should and shouldn't copy.